Article
Clinical value of chip-based digital-PCR platform for the detection of circulating DNA in metastatic colorectal cancer.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Oct 2015
Sefrioui David, Sarafan-Vasseur Nasrin, Beaussire Ludivine, Baretti Marina, Gangloff Alice, Blanchard France, Clatot Florian, Sabourin Jean-Christophe, Sesboüé Richard, Frebourg Thierry, Michel Pierre, Di Fiore Frédéric
Abstract excerpt
BACKGROUND: The detection of circulating DNA is considered a promising strategy in cancer patients. Digital PCR has emerged as a sensitive method able to quantify both circulating free and tumour DNA. AIM: The aim of this study was to prospectively evaluate the clinical value of a chip-based digital PCR for the detection of circulating DNA. METHODS: Digital PCR was used in 34 metastatic colorectal cancer patients...
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