Article
Blood circulating tumor DNA for non-invasive genotyping of colon cancer patients.
Molecular oncology - 1 Mar 2016
Siravegna Giulia, Bardelli Alberto
Abstract excerpt
Most solid tumors, including colorectal cancers, shed cell-free DNA (ctDNA) in the blood. ctDNA can be analyzed to generate molecular profiles which capture the heterogeneity of the disease more comprehensively then tumor tissue biopsies. This approach commonly called 'liquid biopsy' can be applied to monitor response to therapy, to assess minimal residual disease and to uncover the emergence of drug resistance....
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