Article
Kv1.3 contains an alternative C-terminal ER exit motif and is recruited into COPII vesicles by Sec24a.
BMC biochemistry - 10 Jul 2015
Spear John M, Koborssy Dolly Al, Schwartz Austin B, Johnson Adam J, Audhya Anjon, Fadool Debra A, Stagg Scott M
Abstract excerpt
BACKGROUND: Potassium channels play a fundamental role in resetting the resting membrane potential of excitable cells. Determining the intracellular trafficking and localization mechanisms of potassium channels provides a platform to fully characterize their maturation and functionality. Previous investigations have discovered residues or motifs that exist in their primary structure, which directly promote...
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