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Kv1.3 K<sup>+</sup>Channel Physiology Assessed by Genetic and Pharmacological Modulation

28 Aug 2022

Abstract excerpt

Potassium channels are widespread over all kingdoms and play an important role in the maintenance of cellular ionic homeostasis. Kv1.3 is a voltage-gated potassium channel of the Shaker family with a wide tissue expression and a well-defined pharmacology. In recent decades, experiments mainly based on pharmacological modulation of Kv1.3 have highlighted its crucial contribution to different fundamental processes...

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PMID: 35998249
DOI: 10.1152/physiol.00010.2022

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