Article
Relationship between three novel SNPs of BRCA1 and canine mammary tumors.
The Journal of veterinary medical science - 1 Nov 2015
Sun Weidong, Yang Xu, Qiu Hengbin, Zhang Di, Wang Huanan, Huang Jian, Lin Degui
Abstract excerpt
The BRCA1 gene plays an important role in the development of human breast cancer, and recent research indicated that genetic variations of BRCA1 are also related to canine mammary tumors (CMTs). Here, using rapid amplification of cDNA ends (RACE), we cloned the 5'- and 3'-UTRs of BRCA1. By direct sequencing of the flanking sequences of the 5'- and 3'-UTRs of BRCA1, three previously unreported single-nucleotide...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.