Article
Promoter mutation and reduced expression of BRCA1 in canine mammary tumors.
Research in veterinary science - 1 Dec 2015
Qiu H B, Sun W D, Yang X, Jiang Q Y, Chen S, Lin D G
Abstract excerpt
Breast cancer 1, early onset (BRCA1) is one of the most important genes in human familial breast cancer, which also plays an important role in canine mammary tumors. The objectives of this study were to determine the promoter sequence of canine BRCA1, to investigate its promoter mutation status and to describe BRCA1 expression pattern in canine mammary tumors. The promoter sequence of canine BRCA1 was acquired by...
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