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Article

Genome-Wide Analysis Identifies Germ-Line Risk Factors Associated with Canine Mammary Tumours.

PLoS genetics - 1 May 2016

Melin Malin, Rivera Patricio, Arendt Maja, Elvers Ingegerd, Murén Eva, Gustafson Ulla, Starkey Mike, Borge Kaja Sverdrup, Lingaas Frode, Häggström Jens, Saellström Sara, Rönnberg Henrik, Lindblad-Toh Kerstin

Abstract excerpt

Canine mammary tumours (CMT) are the most common neoplasia in unspayed female dogs. CMTs are suitable naturally occurring models for human breast cancer and share many characteristics, indicating that the genetic causes could also be shared. We have performed a genome-wide association study (GWAS) in English Springer Spaniel dogs and identified a genome-wide significant locus on chromosome 11 (praw = 5.6x10-7,...

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Identifiers

PMID: 27158822
DOI: 10.1371/journal.pgen.1006029
PMCID: PMC4861258

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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