Article
Mammary tumor development in dogs is associated with BRCA1 and BRCA2.
Cancer research - 15 Nov 2009
Rivera Patricio, Melin Malin, Biagi Tara, Fall Tove, Häggström Jens, Lindblad-Toh Kerstin, von Euler Henrik
Abstract excerpt
Breast cancer is a major contributor to overall morbidity and mortality in women. Several genes predisposing to breast cancer have been identified, but the majority of risk factors remain unknown. Even less is known about the inherited risk factors underlying canine mammary tumors (CMT). Clear breed predispositions exist, with 36% of English springer spaniels (ESS) in Sweden being affected. Here, we evaluate 10...
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