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Article

Identification of genetic variation in 11 candidate genes of canine mammary tumour.

Veterinary and comparative oncology - 1 Dec 2011

Borge K S, Børresen-Dale A L, Lingaas F

Abstract excerpt

The incidence of canine mammary tumours (CMTs) differs significantly between breeds, strongly supporting an influence of genetic risk factors. We aimed at identifying germline genetic variations in mammary tumour-associated genes in dogs and survey whether these might alter the encoded proteins. We sequenced 11 genes (BRCA1, BRCA2, BRIP1, CDH1, CHEK2, EGFR, ESR1, HER2, PTEN, STK11 and TP53) and screened for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22077404
DOI: 10.1111/j.1476-5829.2010.00250.x

Genes

BRCA1
BRCA2
BRIP1
CDH1
CHEK2
EGFR
ESR1
PTEN
STK11

Provenance

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