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Article

Single nucleotide variation in exon 11 of canine BRCA2 in healthy and cancerous mammary tissue.

Veterinary journal (London, England : 1997) - 1 Jun 2010

Hsu Wei-Li, Huang Yi-Hsin, Chang Tien-Jye, Wong Min-Liang, Chang Shih-Chieh

Abstract excerpt

Germline mutations in the BRCA2 tumour suppressor gene are significant risk indicators of breast cancer in women, especially for hereditary breast cancer. The BRCA2 protein interacts via the BRC (breast cancer) domain with RAD51, an essential component of the cellular machinery for the maintenance of genome stability and double strand-breaks repair. Exon 11 is the largest exon of the BRCA2 gene and contains the...

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Source

Identifiers

PMID: 19944633
DOI: 10.1016/j.tvjl.2009.03.022

Genes

BRCA2
RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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