Article
Yeast model identifies ENTPD6 as a potential non-obstructive azoospermia pathogenic gene.
Scientific reports - 8 Jul 2015
Wang Qian, Liu Chao, Tang Chaoming, Guo Huiping, Liu Yujiao, Wang Lina, Zhao Haichao, Shang Yongliang, Wen Yang, Lin Yuan, Zhou Tao, Zhou Zuomin, Dong Wen, Hu Zhibin, Guo Xuejiang, Sha Jiahao, Li Wei
Abstract excerpt
Approximately ten percent of male infertility is caused by non-obstructive azoospermia (NOA), but the etiologies of many NOA remain elusive. Recently, a genome-wide association study (GWAS) of NOA in Han Chinese men was conducted, and only a few genetic variants associated with NOA were found, which might have resulted from genetic heterogeneity. However, those variants that lack genome-wide significance might...
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