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Article

A homozygous missense variant in DND1 causes non-obstructive azoospermia in humans

30 Sept 2022

Abstract excerpt

Non-obstructive azoospermia (NOA) is a severe factor of male infertility; it affects approximately 1% of the global male population and accounts for 40% of male infertility cases. However, the majority of NOA cases remain idiopathic. This is the first study using whole-exome sequencing (WES) to identify a novel missense mutation in the DND1 gene (c.212A>C, p. E71A) from a Pakistani family, that includes three...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 36246621
DOI: 10.3389/fgene.2022.1017302

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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