Back to search

Article

FertilityOnline, a straight pipeline for functional gene annotation and disease mutation discovery, identifies novel infertility causative mutations in <i>SYCE1</i> and <i>STAG3</i>

2020-08-06

Abstract excerpt

Exploring the genetic basis of human infertility is currently under intensive investigation. However, only a handful of genes are validated in animal models as disease-causing genes in infertile men. Thus, to better understand the genetic basis of spermatogenesis in human and to bridge the knowledge gap between human and other animal species, we have constructed FertilityOnline database, which is a resource that i...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
cd5824cc-3d6a-5a52-a60e-e35a1e64038c
DOI
10.1101/2020.08.05.238162
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
FertilityOnline, a straight pipeline for functional gene annotation and disease mutation discovery, identifies novel infertility causative mutations in <i>SYCE1</i> and <i>STAG3</i>DOI 10.1101/2020.08.05.238162
FertilityOnline: A Straightforward Pipeline for Functional Gene Annotation and Disease Mutation Discovery.Semantic proximity
IDDB: a comprehensive resource featuring genes, variants and characteristics associated with infertility.Semantic proximity
Progress in the genetic studies of spermatogenesis abnormalities.Semantic proximity
Migene: an Evidence-based Database of Genes and Phenotypes of Male InfertilitySemantic proximity
SpermatogenesisOnline 1.0: a resource for spermatogenesis based on manual literature curation and genome-wide data miningSemantic proximity
Disorders of spermatogenesisSemantic proximity
Deciphering the Molecular Characteristics of Human Idiopathic Nonobstructive Azoospermia from the Perspective of Germ CellsSemantic proximity
Diverse monogenic subforms of human spermatogenic failureSemantic proximity
Diverse Monogenic Subforms of Human Spermatogenic FailureSemantic proximity
Identification of deleterious variants in patients with male infertility due to idiopathic non-obstructive azoospermiaSemantic proximity
Pathogenic landscape of idiopathic male infertility: new insight towards its regulatory networksSemantic proximity
The Novel Key Genes of Non-obstructive Azoospermia Affect Spermatogenesis: Transcriptomic Analysis Based on RNA-Seq and scRNA-Seq DataSemantic proximity
Select a neighboring publication to make it the new centre.