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Article

Genetics of Azoospermia.

International journal of molecular sciences - 23 Mar 2021

Cioppi Francesca, Rosta Viktoria, Krausz Csilla

Abstract excerpt

Azoospermia affects 1% of men, and it can be due to: (i) hypothalamic-pituitary dysfunction, (ii) primary quantitative spermatogenic disturbances, (iii) urogenital duct obstruction. Known genetic factors contribute to all these categories, and genetic testing is part of the routine diagnostic workup of azoospermic men. The diagnostic yield of genetic tests in azoospermia is different in the different etiological...

Topics

Alleles
Animals
Azoospermia
Biomarkers
Chromosome Deletion
Chromosomes, Human, Y
Female
Genetic Association Studies
Genetic Predisposition to Disease
Genetic Testing
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Spermatogenesis

Exome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 33806855
DOI: 10.3390/ijms22063264
PMCID: PMC8004677

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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