Article
Cytoplasmic LSM-1 protein regulates stress responses through the insulin/IGF-1 signaling pathway in Caenorhabditis elegans.
RNA (New York, N.Y.) - 1 Sept 2015
Cornes Eric, Porta-De-La-Riva Montserrat, Aristizábal-Corrales David, Brokate-Llanos Ana María, García-Rodríguez Francisco Javier, Ertl Iris, Díaz Mònica, Fontrodona Laura, Reis Kadri, Johnsen Robert, Baillie David, Muñoz Manuel J, Sarov Mihail, Dupuy Denis, Cerón Julián
Abstract excerpt
Genes coding for members of the Sm-like (LSm) protein family are conserved through evolution from prokaryotes to humans. These proteins have been described as forming homo- or heterocomplexes implicated in a broad range of RNA-related functions. To date, the nuclear LSm2-8 and the cytoplasmic LSm1-7 heteroheptamers are the best characterized complexes in eukaryotes. Through a comprehensive functional study of the...
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