The Rat Homolog of the Schizophrenia Susceptibility Gene ZNF804A Is Highly Expressed during Brain Development, Particularly in Growth Cones.

doi:10.1371/journal.pone.0132456

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Article

The Rat Homolog of the Schizophrenia Susceptibility Gene ZNF804A Is Highly Expressed during Brain Development, Particularly in Growth Cones.

PloS one - 1 Jan 2015

Hinna Katja Hvid, Rich Karen, Fex-Svenningsen Åsa, Benedikz Eirikur

Abstract excerpt

A single nucleotide polymorphism in the ZNF804A gene, rs1344706, is associated with schizophrenia. The polymorphism has been suggested to alter fetal expression of ZNF804A. It has also been reported to be associated with altered cortical functioning and neural connectivity in the brain. Since developmental mechanisms are suggested in the pathophysiology for schizophrenia, expression of Zfp804A, the rat homolog of...

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PMID: 26148198
DOI: 10.1371/journal.pone.0132456
PMCID: PMC4493006

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