Article
Evidence that schizophrenia risk variation in the ZNF804A gene exerts its effects during fetal brain development.
The American journal of psychiatry - 1 Dec 2012
Hill Matthew J, Bray Nicholas J
Abstract excerpt
OBJECTIVE: The single-nucleotide polymorphism rs1344706, located within an intron of the ZNF804A gene, exhibits genome-wide significant association with schizophrenia. Although genotype at rs1344706 is associated with altered functional brain connectivity, the molecular mechanisms mediating its association with schizophrenia have not been clearly defined. Given its location in noncoding sequence, the authors...
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