Article
Expression of ZNF804A in human brain and alterations in schizophrenia, bipolar disorder, and major depressive disorder: a novel transcript fetally regulated by the psychosis risk variant rs1344706.
JAMA psychiatry - 1 Oct 2014
Tao Ran, Cousijn Helena, Jaffe Andrew E, Burnet Philip W J, Edwards Freya, Eastwood Sharon L, Shin Joo Heon, Lane Tracy A, Walker Mary A, Maher Brady J, Weinberger Daniel R, Harrison Paul J, Hyde Thomas M, Kleinman Joel E
Abstract excerpt
IMPORTANCE: The single-nucleotide polymorphism rs1344706 in the zinc finger protein 804A gene (ZNF804A) shows genome-wide association with schizophrenia and bipolar disorder. Little is known regarding the expression of ZNF804A and the functionality of rs1344706. OBJECTIVES: To characterize ZNF804A expression in human brain and to investigate how it changes across the life span and how it is affected by rs1344706,...
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