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Article

Molecular backgrounds of ERAP1 downregulation in cervical carcinoma.

Analytical cellular pathology (Amsterdam) - 1 Jan 2015

Mehta Akash M, Osse Michelle, Kolkman-Uljee Sandra, Fleuren Gert Jan, Jordanova Ekaterina S

Abstract excerpt

The antigen processing machinery (APM) plays an important role in immune recognition of virally infected and transformed cells. Defective expression of the APM component ERAP1 is associated with progression and poor clinical outcome in cervical carcinoma. However, the underlying mechanisms of ERAP1 protein downregulation remain to be established. We investigated ERAP1 mRNA expression levels in 14 patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26146606
DOI: 10.1155/2015/367837
PMCID: PMC4471254

Genes

ERAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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