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Article

Frequency of down-regulation of individual HLA-A and -B alleles in cervical carcinomas in relation to TAP-1 expression.

British journal of cancer - 1 Aug 1995

Keating P J, Cromme F V, Duggan-Keen M, Snijders P J, Walboomers J M, Hunter R D, Dyer P A, Stern P L

Abstract excerpt

The development of cervical carcinoma is strongly associated with specific types of human papillomaviruses (HPVs). A role for cellular immunity in cervical disease is supported by the increased occurrence of HPV-associated lesions in immunosuppressed individuals. Upon viral infection or malignant transformation, ensuing alterations in gene expression result in the generation of novel sets of peptides which can...

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Identifiers

PMID: 7640226
DOI: 10.1038/bjc.1995.346
PMCID: PMC2033975

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Frequency of down-regulation of individual HLA-A and -B alleles in cervical carcinomas in relation to TAP-1 expression.PMID 7640226Read ↗

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Multiple mechanisms underlie HLA dysregulation in cervical cancer.Semantic proximity Read ↗

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No association of TAP1 and TAP2 genes polymorphism with risk of cervical cancer in north Indian population.Semantic proximity Read ↗

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Multiple genetic alterations cause frequent and heterogeneous human histocompatibility leukocyte antigen class I loss in cervical cancer.Semantic proximity Read ↗

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