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Article

Genetic variation of antigen processing machinery components and association with cervical carcinoma.

Genes, chromosomes & cancer - 1 Jun 2007

Mehta Akash M, Jordanova Ekaterina S, van Wezel Tom, Uh Hae-Won, Corver Willem E, Kwappenberg Kitty M C, Verduijn Willem, Kenter Gemma G, van der Burg Sjoerd H, Fleuren Gert J

Abstract excerpt

The antigen processing machinery (APM) plays an important role in immune recognition of virally infected and transformed cells. Defective expression of several APM components is associated with progression and clinical outcome in cervical carcinoma. Genetic variation in the genes encoding APM components is known to be associated with risk of occurrence of several malignancies. However, only limited evidence...

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Source

Identifiers

PMID: 17366619
DOI: 10.1002/gcc.20441

Genes

ERAP1
TAP2
TAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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