Article
Polymorphisms in endoplasmic reticulum aminopeptidase genes are associated with cervical cancer risk in a Chinese Han population.
BMC cancer - 22 Apr 2020
Li Chuanyin, Li Yaheng, Yan Zhiling, Dai Shuying, Liu Shuyuan, Wang Xia, Wang Jun, Zhang Xinwen, Shi Li, Yao Yufeng
Abstract excerpt
BACKGROUND: Antigen-processing machinery molecules play crucial roles in infectious diseases and cancers. Studies have shown that polymorphisms in endoplasmic reticulum aminopeptidase (ERAP) genes can influence the enzymatic activity of ERAP proteins and are associated with the risk of diseases. In the current study, we evaluated the influence of ERAP gene (ERAP1 and ERAP2) polymorphisms on susceptibility to...
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