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Article

Deficient expression of components of the MHC class I antigen processing machinery in human cervical carcinoma.

International journal of oncology - 1 Dec 2001

Ritz U, Momburg F, Pilch H, Huber C, Maeurer M J, Seliger B

Abstract excerpt

In cervical carcinomas abnormalities in the MHC class I surface expression are a frequent event, which are often associated with the deficient expression of the peptide transporter subunit TAP1 thereby resulting in impaired T cell response. In order to understand the role of other components of the MHC class I antigen processing machinery (APM) in the immune escape, 16 surgically removed primary cervical...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class I

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Source

Identifiers

PMID: 11713591
DOI: 10.3892/ijo.19.6.1211

Genes

TAP1
TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Deficient expression of components of the MHC class I antigen processing machinery in human cervical carcinoma.PMID 11713591Read ↗

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