Article
Clinical implications of telomere dysfunction in lung fibrosis.
Current opinion in pulmonary medicine - 1 Sept 2018
Molina-Molina Maria, Borie Raphael
Abstract excerpt
PURPOSE OF REVIEW: Telomere attrition has been proposed as one of the aging hallmarks in pulmonary fibrosis. Telomere shortening and telomerase gene mutations have been widely evaluated in recent years. Reduced telomere length may be identified in a quarter of patients with sporadic idiopathic pulmonary fibrosis (IPF) and half of those cases with family aggregation. However, telomere studies have not transferred...
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