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Telomere Abnormalities in the Pathobiology of Idiopathic Pulmonary Fibrosis

16 Aug 2019

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) occurs primarily in older adults and the incidence is clearly associated with aging. This disease seems to be associated with several hallmarks of aging, including telomere attrition and cellular senescence. Increasing evidence suggests that abnormalities involving telomeres and their proteome play a significant role in the pathobiology of IPF. The aim of this study is to...

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PMID: 31426295
DOI: 10.3390/jcm8081232

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