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High-glucose diets have sex-specific effects on aging in C. elegans: toxic to hermaphrodites but beneficial to males

8 Jun 2015

Abstract excerpt

Diet and sex are important determinants of lifespan. In humans, high sugar diets, obesity, and type 2 diabetes correlate with decreased lifespan, and females generally live longer than males. The nematode Caenorhabditis elegans is a classical model for aging studies, and has also proven useful for characterizing the response to high-glucose diets. However, studies on male animals are lacking. We found a...

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PMID: 26143626
DOI: 10.18632/aging.100759

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