Article
Fecal IgA, Antigen Absorption, and Gut Microbiome Composition Are Associated With Food Antigen Sensitization in Genetically Susceptible Mice.
Frontiers in immunology - 1 Jan 2020
Smeekens Johanna M, Johnson-Weaver Brandi T, Hinton Andrew L, Azcarate-Peril M Andrea, Moran Timothy P, Immormino Robert M, Kesselring Janelle R, Steinbach Erin C, Orgel Kelly A, Staats Herman F, Burks A Wesley, Mucha Peter J, Ferris Martin T, Kulis Michael D
Abstract excerpt
Food allergy is a potentially fatal disease affecting 8% of children and has become increasingly common in the past two decades. Despite the prevalence and severe nature of the disease, the mechanisms underlying sensitization remain to be further elucidated. The Collaborative Cross is a genetically diverse panel of inbred mice that were specifically developed to study the influence of genetics on complex...
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