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Article

Clinical Utility of a Coronary Heart Disease Risk Prediction Gene Score in UK Healthy Middle Aged Men and in the Pakistani Population.

PloS one - 1 Jan 2015

Beaney Katherine E, Cooper Jackie A, Ullah Shahid Saleem, Ahmed Waqas, Qamar Raheel, Drenos Fotios, Crockard Martin A, Humphries Steve E

Abstract excerpt

BACKGROUND: Numerous risk prediction algorithms based on conventional risk factors for Coronary Heart Disease (CHD) are available but provide only modest discrimination. The inclusion of genetic information may improve clinical utility. METHODS: We tested the use of two gene scores (GS) in the prospective second Northwick Park Heart Study (NPHSII) of 2775 healthy UK men (284 cases), and Pakistani case-control...

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Identifiers

PMID: 26133560
DOI: 10.1371/journal.pone.0130754
PMCID: PMC4489836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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