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Chromosome 9p21.3 coronary heart disease locus genotype and prospective risk of CHD in healthy middle-aged men.

Clinical chemistry - 1 Mar 2008

Talmud Philippa J, Cooper Jackie A, Palmen Jutta, Lovering Ruth, Drenos Fotios, Hingorani Aroon D, Humphries Steve E

Abstract excerpt

BACKGROUND: We investigated whether chromosome 9p21.3 single-nucleotide polymorphisms (SNPs), identified in coronary heart disease (CHD) genome-wide association scans, added significantly to the predictive utility for CHD of conventional risk factors (CRF) in the Framingham risk score (FRS) algorithm. METHODS: In the Northwick Park Heart Study II of 2742 men (270 CHD events occurring during a 15-year prospective...

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PMID: 18250146
DOI: 10.1373/clinchem.2007.095489

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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