Article
Genetic variants at chromosome 9p21 and risk of first versus subsequent coronary heart disease events: a systematic review and meta-analysis.
Journal of the American College of Cardiology - 3 Jun 2014
Patel Riyaz S, Asselbergs Folkert W, Quyyumi Arshed A, Palmer Tom M, Finan Chris I, Tragante Vinicius, Deanfield John, Hemingway Harry, Hingorani Aroon D, Holmes Michael V
Abstract excerpt
OBJECTIVES: The purpose of this analysis was to compare the association between variants at the chromosome 9p21 locus (Ch9p21) and risk of first versus subsequent coronary heart disease (CHD) events through systematic review and meta-analysis. BACKGROUND: Ch9p21 is a recognized risk factor for a first CHD event. However, its association with risk of subsequent events in patients with established CHD is less...
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