Article
Alterations in Skeletal Muscle Oxidative Phenotype in Mice Exposed to 3 Weeks of Normobaric Hypoxia.
Journal of cellular physiology - 1 Feb 2016
Slot Ilse G M, Schols Annemie M W J, de Theije Chiel C, Snepvangers Frank J M, Gosker Harry R
Abstract excerpt
Skeletal muscle of patients with chronic respiratory failure is prone to loss of muscle mass and oxidative phenotype. Tissue hypoxia has been associated with cachexia and emphysema in humans. Experimental research on the role of hypoxia in loss of muscle oxidative phenotype, however, has yielded inconsistent results. Animal studies are frequently performed in young animals, which may hinder translation to...
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