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Article

Phenotypic and metabolic features of mouse diaphragm and gastrocnemius muscles in chronic lung carcinogenesis: influence of underlying emphysema.

Journal of translational medicine - 23 Aug 2016

Salazar-Degracia Anna, Blanco David, Vilà-Ubach Mònica, de Biurrun Gabriel, de Solórzano Carlos Ortiz, Montuenga Luis M, Barreiro Esther

Abstract excerpt

BACKGROUND: Muscle wasting negatively impacts the progress of chronic diseases such as lung cancer (LC) and emphysema, which are in turn interrelated. OBJECTIVES: We hypothesized that muscle atrophy and body weight loss may develop in an experimental mouse model of lung carcinogenesis, that the profile of alterations in muscle fiber phenotype (fiber type composition and morphometry, muscle structural alterations,...

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Identifiers

PMID: 27549759
DOI: 10.1186/s12967-016-1003-9
PMCID: PMC4994253

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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