Article
Effects of aging and obesity on respiratory muscle phenotype in Zucker rats.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Sept 1996
Powers S K, Farkas G A, Demirel H, Coombes J, Fletcher L, Hughes M G, Hodge K, Dodd S L, Schlenker E H
Abstract excerpt
Because obesity results in an increased work of breathing, we tested the hypothesis that the oxidative properties and myosin heavy chain (MHC) isoform profiles in respiratory muscles would differ between lean and obese animals. Furthermore, we postulated that obesity-related changes in respiratory muscles would be independent of age. To test these hypothesis, samples of the costal diaphragm, crural diaphragm, and...
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