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Article

The Role of Mitochondrial DNA Variation in Age-Related Decline in Gait Speed Among Older Men Living With Human Immunodeficiency Virus.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 16 Aug 2018

Sun Jing, Brown Todd T, Samuels David C, Hulgan Todd, D'Souza Gypsyamber, Jamieson Beth D, Erlandson Kristine M, Martinson Jeremy, Palella Frank J, Margolick Joseph B, Kirk Gregory D, Schrack Jennifer A

Abstract excerpt

Background: Age-related gait speed decline is accelerated in men with human immunodeficiency virus (HIV). Mitochondrial genetic variation is associated with frailty and mortality in the general population and may provide insight into mechanisms of functional decline in people aging with HIV. Methods: Gait speed was assessed semiannually in the Multicenter AIDS Cohort Study. Mitochondrial DNA (mtDNA) haplogroups...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29481608
DOI: 10.1093/cid/ciy151
PMCID: PMC6093993

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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