Article
Mitochondrial DNA haplogroups influence AIDS progression.
AIDS (London, England) - 30 Nov 2008
Hendrickson Sher L, Hutcheson Holli B, Ruiz-Pesini Eduardo, Poole Jason C, Lautenberger James, Sezgin Efe, Kingsley Lawrence, Goedert James J, Vlahov David, Donfield Sharyne, Wallace Douglas C, O'Brien Stephen J
Abstract excerpt
OBJECTIVE: Mitochondrial function plays a role in both AIDS progression and HAART toxicity; therefore, we sought to determine whether mitochondrial DNA variation revealed novel AIDS restriction genes, particularly as mitochondrial DNA single-nucleotide polymorphisms are known to influence regulat...
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