Article
Association between C1GALT1 variants and genetic susceptibility to IgA nephropathy in Uygur.
Genetics and molecular research : GMR - 22 May 2015
Li W L, Lu C
Abstract excerpt
Immunoglobulin A (IgA) nephropathy (IgAN) is a common form of primary glomerulonephritis characterized by diffuse glomerular mesangial IgA1 deposition leading to mesangial proliferation and chronic glomerular inflammation. Analyses of serum IgA1 from IgAN patients revealed abnormal galactosylation of the O-linked carbohydrate moieties of IgA that may result from altered activity in the core of 1...
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