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Article

The Association of rs1047763 and rs1008898 of C1GALT1 with IgA Nephropathy Risk: A Global Meta-Analysis.

Monoclonal antibodies in immunodiagnosis and immunotherapy - 1 Jun 2017

Nie Ruili, Cheng Guixue, Zhang Jin, Dong Yu, Wang Chen, Liu Jianhua, Qin Xiaosong

Abstract excerpt

IgA nephropathy (IgAN) is a globally common primary glomerulonephritis characterized by an elevated level of serum IgA and immune complex deposition in the mesangial area. In the serum of patients with IgAN, the hinge region of IgA1 immunoglobulin contains aberrantly glycosylated O-glycans deficient in galactose, which is normally added to the core 1 O-glycan structure by core 1 synthase,...

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Identifiers

PMID: 28636500
DOI: 10.1089/mab.2016.0050

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The Association of rs1047763 and rs1008898 of C1GALT1 with IgA Nephropathy Risk: A Global Meta-Analysis.PMID 28636500Read ↗

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