Article
ST6GAL1 polymorphisms influence susceptibility and progression of IgA nephropathy in a Chinese Han population.
Immunobiology - 1 Jul 2020
Fu Dongying, Zhong Zhong, Shi Dianchun, Peng Yuan, Li Bin, Wang Dan, Guo Lin, Li Zhijian, Mao Haiping, Yu Xueqing, Li Ming
Abstract excerpt
BACKGROUND: ST6GAL1 has been identified as a novel susceptibility gene for IgA nephropathy (IgAN) in a previous genome-wide association study. The present study is aimed at exploring whether the genetic polymorphisms of ST6GAL1 gene correlate with IgAN susceptibility, clinical phenotypes and progression in a Chinese Han population. METHODS: Twenty-six single nucleotide polymorphisms (SNPs) of ST6GAL1 were...
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