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Mitochondrial D310 instability in Chinese lung cancer patients.

Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis - 1 Jan 2016

Chen Xian-Zhong, Fang Yu, Shi Yan-Hai, Cui Jing-Hui, Li Long-Yan, Xu Yong-Chen, Ling Bin

Abstract excerpt

To characterize the somatic mutation spectrum of mitochondrial DNA at D310 in Chinese lung cancer patients and evaluate its potential significance in Chinese lung cancer diagnosis, in this study, 237 samples, including lung tumor, adjacent normal tissue and blood samples of 79 lung cancer patients were analyzed. By comparing sequences of D310 between lung cancer tissues, adjacent normal tissue and blood samples,...

Topics

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Biomarkers, Tumor
DNA, Mitochondrial
DNA, Neoplasm
Genomic Instability
Lung Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25010070
DOI: 10.3109/19401736.2014.936426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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