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Article

RECQL: a new breast cancer susceptibility gene.

Cell cycle (Georgetown, Tex.) - 1 Jan 2015

Banerjee Taraswi, Brosh Robert M

Abstract excerpt

Identifying and characterizing novel genetic risk factors for BRCA1/2 negative breast cancers is highly relevant for early diagnosis and development of a management plan. Mutations in a number of DNA repair genes have been associated with genomic instability and development of breast and various other cancers. Whole exome sequencing efforts by 2 groups have led to the discovery in distinct populations of multiple...

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Topics

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Share to BRCA1 Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Genomic Instability

Share to High-Throughput Nucleotide Sequencing

Share to Recombinational DNA Repair

Share to RecQ Helicases

Source

Open in PubMed Open full text

Identifiers

PMID: 26125302
DOI: 10.1080/15384101.2015.1066539
PMCID: PMC4825713

Genes

RECQL
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RECQL: a new breast cancer susceptibility gene.PMID 26125302Read ↗

Mutations in RECQL Gene Are Associated with Predisposition to Breast Cancer.Semantic proximity Read ↗

Germline RECQL mutations are associated with breast cancer susceptibility.Semantic proximity Read ↗

RECQL5: Another DNA helicase potentially involved in hereditary breast cancer susceptibilitySemantic proximity Read ↗

Germline RECQL mutations in high risk Chinese breast cancer patients.Semantic proximity Read ↗

RecQ Helicase Somatic Alterations in CancerSemantic proximity Read ↗

RECQL4 helicase has oncogenic potential in sporadic breast cancers.Semantic proximity Read ↗

Genome-Wide Analysis Unveils DNA Helicase RECQ1 as a Regulator of Estrogen Response Pathway in Breast Cancer Cells.Semantic proximity Read ↗

RECQ1 Helicase in Genomic Stability and Cancer.Semantic proximity Read ↗

Genome-wide investigations on regulatory functions of RECQ1 helicase.Semantic proximity Read ↗

Human RecQ Helicases in DNA Double-Strand Break RepairSemantic proximity Read ↗

Transcriptional regulation by a RecQ helicase.Semantic proximity Read ↗

RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1.Semantic proximity Read ↗

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