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Article

Transcriptional regulation by a RecQ helicase.

Methods in enzymology - 1 Jan 2022

Debnath Subrata, Lu Xing, Sharma Sudha

Abstract excerpt

RecQ helicases participate in a variety of DNA metabolic processes through their multiple biochemical activities. In vitro characterization and cellular studies have suggested that RECQ1 (also known as RECQL or RECQL1) performs its diverse functions through specific interactions with DNA and protein partners. We have taken an unbiased approach to determine the contribution of RECQ1 in genome maintenance and as a...

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Identifiers

PMID: 35965009
DOI: 10.1016/bs.mie.2022.03.057
PMCID: PMC9379128

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