Article
Genome-wide investigations on regulatory functions of RECQ1 helicase.
Methods (San Diego, Calif.) - 1 Aug 2022
Debnath Subrata, Lu Xing, Lal Ashish, Sharma Sudha
Abstract excerpt
DNA helicase RECQ1 (also known as RECQL or RECQL1) is a candidate breast cancer susceptibility gene significantly correlated with clinical outcomes of sporadic breast cancer patients. Prior studies have suggested that RECQ1 maintains genomic stability by regulating a wide variety of core cellular functions including DNA replication, DNA damage response, and transcription. However, it is unclear which, if any, of...
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