The comparison of some pharmacokinetic parameters of sulphadimethoxine estimated by high performance liquid chromatography and three spectrophotometric methods.

doi:10.1007/BF03190097

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Article

The comparison of some pharmacokinetic parameters of sulphadimethoxine estimated by high performance liquid chromatography and three spectrophotometric methods.

European journal of drug metabolism and pharmacokinetics - 1 Jan 2000

Klimowicz A

Abstract excerpt

The influence of the method used for determination of drugs in biological fluids on the pharmacokinetic parameters of sulphadimethoxine was investigated in healthy adult human subjects. Sulphonamide concentrations were determined by four chemical methods: high performance liquid chromatography (H...

Topics

Acetylation
Adult
Chromatography, High Pressure Liquid
Creatinine
Female
Half-Life
Humans
Male
Middle Aged
Phenotype
Smoking
Spectrophotometry
Sulfadimethoxine

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