Article
[Biotransformation of phenazone and sulfadimidine as markers of liver metabolism of drug and xenobiotic oxidation and acetylation in women with breast cancer].
Przeglad lekarski - 1 Jan 1997
Orzechowska-Juzwenko K, Wiela-Hojeńska A, Milejski P, Cieślińska A, Hudziec P, Adamska M
Abstract excerpt
The aim of our study was to determine phenazone pharmacokinetics as an index of hepatic microsomal enzymes activity and acetylation phenotype in women with breast cancer. Phenazone test was made in 41 women with breast cancer and in 25 healthy women as a control group. Acetylation phenotype was m...
Topics
- Acetylation
- Adult
- Aged
- Anti-Infective Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antipyrine
- Biomarkers, Tumor
- Breast Neoplasms
- Disease Susceptibility
- Female
- Half-Life
- Humans
- Microsomes, Liver
- Middle Aged
- Oxidation-Reduction
- Phenotype
- Sulfamethazine