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Article

Phenotyping with sulfasalazine - time dependence and relation to NAT2 pharmacogenetics.

International journal of clinical pharmacology and therapeutics - 1 Jan 2010

Kuhn U D, Anschütz M, Schmücker K, Schug B S, Hippius M, Blume H H

Abstract excerpt

OBJECTIVE: N-acetyltransferase 2 (NAT2) genotype-phenotype relation with sulfasalazine as probe drug by means of detailed genotype analysis and kinetic data evaluation. BACKGROUND: Though phenotype analysis of sulfasalazine metabolism has been described before, genotype investigations in this regard are scarce. The influence of different single point mutations on the metabolism of the sulfasalazine metabolite...

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Source

Identifiers

PMID: 20040334
DOI: 10.5414/cpp48001

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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