Article
Association between IL7RA polymorphisms and the successful therapy against HCV in HIV/HCV-coinfected patients.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Feb 2015
Guzmán-Fulgencio M, Berenguer J, Pineda-Tenor D, Jiménez-Sousa M A, García-Álvarez M, Aldámiz-Echevarria T, Carrero A, Diez C, Tejerina F, Vázquez S, Briz V, Resino S
Abstract excerpt
Interleukin-7 (IL-7) is a critical factor in maintaining or inducing effective antiviral CD4+ and CD8+ T-cell responses. The aim of this study was to examine the association of interleukin-7 receptor-α (IL7RA) polymorphisms with a sustained virologic response (SVR) after hepatitis C virus (HCV) therapy with pegylated interferon-alpha plus ribavirin (pegIFNα/ribavirin) in 177 human immunodeficiency virus...
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