Article
Variant of BCL3 gene is strongly associated with five-year survival of non-small-cell lung cancer patients.
Lung cancer (Amsterdam, Netherlands) - 1 Sept 2015
Dimitrakopoulos Foteinos-Ioannis D, Antonacopoulou Anna G, Kottorou Anastasia, Marousi Stella, Koukourikou Ioulia, Kalofonou Melpomeni, Panagopoulos Nikolaos, Scopa Chrisoula, Dougenis Dimitrios, Papadaki Helen, Papavassiliou Athanasios G, Kalofonos Haralabos P
Abstract excerpt
OBJECTIVES: BCL3, a known atypical IκB family member, has been documented to be upregulated in hematological malignancies and in some solid tumors, functioning as a crucial player in tumor development. Recently, rs8100239, a tag-Single Nucleotide Polymorphism (SNP) in BCL3 (T>A) has been identified, but there are no data regarding its involvement in non-small-cell lung cancer (NSCLC) initiation and progression....
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