Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Promoter -202 A/C polymorphism of insulin-like growth factor binding protein-3 gene and non-small cell lung cancer risk.

International journal of cancer - 15 Jan 2006

Moon Jin Wook, Chang Yoon Soo, Ahn Chul Woo, Yoo Kyeong Nam, Shin Ju Hye, Kong Jee Hyun, Kim Young Sam, Chang Joon, Kim Sung Kyu, Kim Hee Jung, Kim Se Kyu

Abstract excerpt

Insulin-like growth factor binding protein-3 (IGFBP-3) inhibits the mitogenic and antiapoptotic activity of insulin-like growth factor (IGF) by blocking the binding of IGF to its receptor. However, under certain circumstances, IGFBP-3 can enhance the activity of IGF by protecting IGF from degrada...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Carcinoma, Non-Small-Cell Lung
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Insulin-Like Growth Factor Binding Protein 3

Share to Lung Neoplasms

Share to Polymorphism, Genetic

Share to Promoter Regions, Genetic

Share to Risk Factors

Source

Identifiers

PMID: 16049980
DOI: 10.1002/ijc.21339

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16049980-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Promoter -202 A/C polymorphism of insulin-like growth factor binding protein-3 gene and non-small cell lung cancer risk.PMID 16049980Read ↗

Single nucleotide polymorphisms of IGFBP-3 gene and lung cancer risk in a Korean population.Semantic proximity Read ↗

Association between insulin-like growth factor binding protein-3 promoter polymorphism of -1590 C>A and lung cancer susceptibility in a Chinese Han population.Semantic proximity Read ↗

Impact of the IGFBP3 A-202C polymorphism on susceptibility and clinicopathologic features of breast cancer.Semantic proximity Read ↗

A 3'-untranslated region polymorphism in IGF1 predicts survival of non-small cell lung cancer in a Chinese population.Semantic proximity Read ↗

Insulin-like growth factor binding protein-3 (IGFBP-3) genetic variant and the risk of esophageal squamous cell carcinoma in a Chinese population.Semantic proximity Read ↗

Genetic polymorphisms in the IGFBP3 gene: association with breast cancer risk and blood IGFBP-3 protein levels among Chinese women.Semantic proximity Read ↗

Phenotypes and genotypes of insulin-like growth factor 1, IGF-binding protein-3 and cancer risk: evidence from 96 studies.Semantic proximity Read ↗

IGFBP3 A-202C polymorphism and breast cancer susceptibility: a meta-analysis involving 33,557 cases and 45,254 controls.Semantic proximity Read ↗

IGFBP3 polymorphisms and risk of cancer: a meta-analysis.Semantic proximity Read ↗

Prostate cancer risk in relation to a single nucleotide polymorphism in the insulin-like growth factor-binding protein-3 (IGFBP3) gene: a meta-analysis.Semantic proximity Read ↗

Association between the IGFBP-3 rs2854744 polymorphism and cancer risk: a meta-analysis.Semantic proximity Read ↗

Polymorphic variation at the -202 locus in IGFBP3: Influence on serum levels of insulin-like growth factors, interaction with plasma retinol and vitamin D and breast cancer risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.