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Article

[Genetic Polymorphisms in Wnt Signaling Pathway and Acute Leukemia].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition - 1 May 2015

Zhang Liang-jun, Zhou Juan, Ye Yuan-xin, Lu Xiao-jun, Jiang Hong, Mao Zhi-gang, Zeng Su-gen, Ying Bin-wu

Abstract excerpt

OBJECTIVE: To determine the impacts of Wnt signaling pathway products-polymorphisms of rs4135385, rs11079571 and rs7832767 located in β-catenin gene (CTNNB1), Axin gene (AXIN2), and secreted frizzled-related protein gene (SFRP1) on the risk and treatment outcomes of acute leukemia. METHODS: Bone marrows (volume 1-1. 5 mL) were collected from 372 untreated patients with acute myeloid leukemia (AML) or acute...

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Topics

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Share to Axin Protein
Share to beta Catenin
Share to Intercellular Signaling Peptides and Proteins
Share to Leukemia, Myeloid, Acute
Share to Membrane Proteins
Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma
Share to Remission Induction
Share to Wnt Signaling Pathway

Source

Identifiers

PMID: 26121862

Genes

AXIN2
CTNNB1
SFRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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