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The multiple ways Wnt signaling contributes to acute leukemia pathogenesis

23 Jun 2020

Abstract excerpt

Abstract WNT proteins constitute a very conserved family of secreted glycoproteins that act as short-range ligands for signaling with critical roles in hematopoiesis, embryonic development, and tissue homeostasis. These proteins transduce signals via the canonical pathway, which is β-catenin-mediated and better-characterized, or via more diverse noncanonical pathways that are β-catenin independent and comprise...

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PMID: 32573851
DOI: 10.1002/jlb.2mr0420-707r

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